PittsburghV1, Canada, Analysis, bibRecord, 000215

Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial

Identifieur interne : 000215 ( Canada/Analysis ); précédent : 000214; suivant : 000216

Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial

Auteurs : Ronald J. Krone [États-Unis] ; Andrew D. Althouse [États-Unis] ; Jacqueline Tamis-Holland ; Lakshmi Venkitachalam [États-Unis] ; Arturo Campos [Mexique] ; Alan Forker [États-Unis] ; Alice K. Jacobs [États-Unis] ; Salvador Ocampo [Mexique] ; George Steiner [Canada] ; Francisco Fuentes [États-Unis] ; Ivan R. Pena Sing [États-Unis] ; Maria Mori Brooks [États-Unis]

Source :

The Canadian journal of cardiology [ 0828-282X ] ; 2014.

RBID : PMC:4265566

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Angine de poitrine (), Angine de poitrine (diagnostic), Coronarographie, Diabète de type 2 (), Diabète de type 2 (sang), Facteurs temps, Femelle, Glycémie (métabolisme), Humains, Hémoglobine A glycosylée (métabolisme), Mâle, Revascularisation myocardique (), Résultat thérapeutique, Électrocardiographie, Études de suivi.
MESH :
- diagnostic : Angine de poitrine.
- métabolisme : Glycémie, Hémoglobine A glycosylée.
- sang : Diabète de type 2.
- Adulte d'âge moyen, Angine de poitrine, Coronarographie, Diabète de type 2, Facteurs temps, Femelle, Humains, Mâle, Revascularisation myocardique, Résultat thérapeutique, Électrocardiographie, Études de suivi.

English descriptors

KwdEn :
- Angina Pectoris (complications), Angina Pectoris (diagnosis), Angina Pectoris (surgery), Blood Glucose (metabolism), Coronary Angiography, Diabetes Mellitus, Type 2 (blood), Diabetes Mellitus, Type 2 (complications), Electrocardiography, Female, Follow-Up Studies, Hemoglobin A, Glycosylated (metabolism), Humans, Male, Middle Aged, Myocardial Revascularization (methods), Time Factors, Treatment Outcome.
MESH :
- chemical , metabolism : Blood Glucose, Hemoglobin A, Glycosylated.
- blood : Diabetes Mellitus, Type 2.
- complications : Angina Pectoris, Diabetes Mellitus, Type 2.
- diagnosis : Angina Pectoris.
- methods : Myocardial Revascularization.
- surgery : Angina Pectoris.
- Coronary Angiography, Electrocardiography, Female, Follow-Up Studies, Humans, Male, Middle Aged, Time Factors, Treatment Outcome.

Abstract

Background

The 2012 Guidelines for Diagnosis and Management of Patients with Stable Ischemic Heart Disease recommend intensive antianginal and risk factor treatment (OMT) before considering revascularization to relieve symptoms. The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized patients with ischemic heart disease and anatomy suitable to revascularization to 1): initial OMT with revascularization if needed or 2): initial revascularization plus OMT, and found no difference in major cardiovascular events. Ultimately, however, 37.9% of the OMT group was revascularized (crossed over) during the 5 year follow-up period.

METHODS

Data from the 1192 patients randomized to OMT were analyzed to identify subgroups where the incidence of revascularization was so high that direct revascularization without a trial period could be justified. Multivariate logistic, Cox regression models of baseline data and a landmark analysis of participants not revascularized at six months were constructed.

RESULTS

The models using only data available at the time of study entry had limited predictive value for revascularization by 6 months or by 5 years; however, the model incorporating severity of angina during the first 6 months could better predict revascularization (C statistic = .789).

CONCLUSIONS

With the possible exception of patients with severe angina and proximal LAD disease, this analysis supports the recommendation of the 2012 GUIDELINES for a trial of OMT prior to revascularization. Patients could NOT be identified at the time of catheterization, but a short period of close follow-up during OMT identified the nearly 40% of patients who underwent revascularization.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265566

DOI: 10.1016/j.cjca.2014.07.748
PubMed: 25475464
PubMed Central: 4265566

Affiliations:

Links to Exploration step

PMC:4265566

Le document en format XML

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<author><name sortKey="Ocampo, Salvador" sort="Ocampo, Salvador" uniqKey="Ocampo S" first="Salvador" last="Ocampo">Salvador Ocampo</name>
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<wicri:regionArea>Department of Cardiology, Hospital de Especialidades. Centro Medico La Raza, IMSS. Mexico City</wicri:regionArea>
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<author><name sortKey="Steiner, George" sort="Steiner, George" uniqKey="Steiner G" first="George" last="Steiner">George Steiner</name>
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<author><name sortKey="Fuentes, Francisco" sort="Fuentes, Francisco" uniqKey="Fuentes F" first="Francisco" last="Fuentes">Francisco Fuentes</name>
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<placeName><region type="state">Texas</region>
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<author><name sortKey="Sing, Ivan R Pena" sort="Sing, Ivan R Pena" uniqKey="Sing I" first="Ivan R. Pena" last="Sing">Ivan R. Pena Sing</name>
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<placeName><region type="state">État de New York</region>
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<author><name sortKey="Brooks, Maria Mori" sort="Brooks, Maria Mori" uniqKey="Brooks M" first="Maria Mori" last="Brooks">Maria Mori Brooks</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Angina Pectoris (complications)</term>
<term>Angina Pectoris (diagnosis)</term>
<term>Angina Pectoris (surgery)</term>
<term>Blood Glucose (metabolism)</term>
<term>Coronary Angiography</term>
<term>Diabetes Mellitus, Type 2 (blood)</term>
<term>Diabetes Mellitus, Type 2 (complications)</term>
<term>Electrocardiography</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Hemoglobin A, Glycosylated (metabolism)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Myocardial Revascularization (methods)</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Angine de poitrine ()</term>
<term>Angine de poitrine (diagnostic)</term>
<term>Coronarographie</term>
<term>Diabète de type 2 ()</term>
<term>Diabète de type 2 (sang)</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Glycémie (métabolisme)</term>
<term>Humains</term>
<term>Hémoglobine A glycosylée (métabolisme)</term>
<term>Mâle</term>
<term>Revascularisation myocardique ()</term>
<term>Résultat thérapeutique</term>
<term>Électrocardiographie</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Blood Glucose</term>
<term>Hemoglobin A, Glycosylated</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Diabetes Mellitus, Type 2</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Angina Pectoris</term>
<term>Diabetes Mellitus, Type 2</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Angina Pectoris</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Angine de poitrine</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Myocardial Revascularization</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Glycémie</term>
<term>Hémoglobine A glycosylée</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Diabète de type 2</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Angina Pectoris</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Coronary Angiography</term>
<term>Electrocardiography</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Angine de poitrine</term>
<term>Coronarographie</term>
<term>Diabète de type 2</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Revascularisation myocardique</term>
<term>Résultat thérapeutique</term>
<term>Électrocardiographie</term>
<term>Études de suivi</term>
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<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">The 2012 Guidelines for Diagnosis and Management of Patients with Stable Ischemic Heart Disease recommend intensive antianginal and risk factor treatment (OMT) before considering revascularization to relieve symptoms. The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized patients with ischemic heart disease and anatomy suitable to revascularization to 1): initial OMT with revascularization <underline>if needed</underline>
 or 2): initial revascularization plus OMT, and found no difference in major cardiovascular events. Ultimately, however, 37.9% of the OMT group was revascularized (crossed over) during the 5 year follow-up period.</p>
</sec>
<sec id="S2"><title>METHODS</title>
<p id="P2">Data from the 1192 patients randomized to OMT were analyzed to identify subgroups where the incidence of revascularization was so high that direct revascularization without a trial period could be justified. Multivariate logistic, Cox regression models of baseline data and a landmark analysis of participants not revascularized at six months were constructed.</p>
</sec>
<sec id="S3"><title>RESULTS</title>
<p id="P3">The models using only data available at the time of study entry had limited predictive value for revascularization by 6 months or by 5 years; however, the model incorporating severity of angina during the first 6 months could better predict revascularization (C statistic = .789).</p>
</sec>
<sec id="S4"><title>CONCLUSIONS</title>
<p id="P4">With the possible exception of patients with severe angina and proximal LAD disease, this analysis supports the recommendation of the 2012 GUIDELINES for a trial of OMT prior to revascularization. Patients could NOT be identified at the time of catheterization, but a short period of close follow-up during OMT identified the nearly 40% of patients who underwent revascularization.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list><country><li>Canada</li>
<li>Mexique</li>
<li>États-Unis</li>
</country>
<region><li>Massachusetts</li>
<li>Missouri (État)</li>
<li>Ontario</li>
<li>Pennsylvanie</li>
<li>Texas</li>
<li>État de New York</li>
</region>
<settlement><li>Toronto</li>
</settlement>
<orgName><li>Université de Toronto</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Tamis Holland, Jacqueline" sort="Tamis Holland, Jacqueline" uniqKey="Tamis Holland J" first="Jacqueline" last="Tamis-Holland">Jacqueline Tamis-Holland</name>
</noCountry>
<country name="États-Unis"><region name="Missouri (État)"><name sortKey="Krone, Ronald J" sort="Krone, Ronald J" uniqKey="Krone R" first="Ronald J." last="Krone">Ronald J. Krone</name>
</region>
<name sortKey="Althouse, Andrew D" sort="Althouse, Andrew D" uniqKey="Althouse A" first="Andrew D." last="Althouse">Andrew D. Althouse</name>
<name sortKey="Brooks, Maria Mori" sort="Brooks, Maria Mori" uniqKey="Brooks M" first="Maria Mori" last="Brooks">Maria Mori Brooks</name>
<name sortKey="Forker, Alan" sort="Forker, Alan" uniqKey="Forker A" first="Alan" last="Forker">Alan Forker</name>
<name sortKey="Fuentes, Francisco" sort="Fuentes, Francisco" uniqKey="Fuentes F" first="Francisco" last="Fuentes">Francisco Fuentes</name>
<name sortKey="Jacobs, Alice K" sort="Jacobs, Alice K" uniqKey="Jacobs A" first="Alice K." last="Jacobs">Alice K. Jacobs</name>
<name sortKey="Sing, Ivan R Pena" sort="Sing, Ivan R Pena" uniqKey="Sing I" first="Ivan R. Pena" last="Sing">Ivan R. Pena Sing</name>
<name sortKey="Venkitachalam, Lakshmi" sort="Venkitachalam, Lakshmi" uniqKey="Venkitachalam L" first="Lakshmi" last="Venkitachalam">Lakshmi Venkitachalam</name>
</country>
<country name="Mexique"><noRegion><name sortKey="Campos, Arturo" sort="Campos, Arturo" uniqKey="Campos A" first="Arturo" last="Campos">Arturo Campos</name>
</noRegion>
<name sortKey="Ocampo, Salvador" sort="Ocampo, Salvador" uniqKey="Ocampo S" first="Salvador" last="Ocampo">Salvador Ocampo</name>
</country>
<country name="Canada"><region name="Ontario"><name sortKey="Steiner, George" sort="Steiner, George" uniqKey="Steiner G" first="George" last="Steiner">George Steiner</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Amérique/explor/PittsburghV1/Data/Canada/Analysis

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000215 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Canada/Analysis/biblio.hfd -nk 000215 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Amérique
   |area=    PittsburghV1
   |flux=    Canada
   |étape=   Analysis
   |type=    RBID
   |clé=     PMC:4265566
   |texte=   Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Canada/Analysis/RBID.i   -Sk "pubmed:25475464" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Canada/Analysis/biblio.hfd   \
       | NlmPubMed2Wicri -a PittsburghV1

This area was generated with Dilib version V0.6.38.
Data generation: Fri Jun 18 17:37:45 2021. Site generation: Fri Jun 18 18:15:47 2021

Serveur d'exploration sur Pittsburgh

Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial

Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur Pittsburgh
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.